28436 - Laboratory Animal Science - II
Optional
5.2. Learning tasks
- Lectures: Theoretical classes (20 hours) will be taught in the schedule established by the Faculty.
- Practical classes: A total of 10 hours of practice, distributed in 6 sessions, will be taught in the Laboratory of Physiology, room of Necropsies, Clinic Hospital or in the Computer room. Dates of the practices will be announced in advance, in such a way that the students choose for the date that best suits them.
Summary table of teaching-learning activities
|
ACTIVITY
|
ATTENDANCE HOURS
|
FACTOR
|
SELF STUDY HOURS
|
TOTAL
|
|
Lectures
|
20
|
1,5
|
30
|
50
|
|
Practices
|
10
|
1
|
10
|
20
|
|
Exams
|
|
|
3
|
3
|
|
Total
|
30
|
|
43
|
73
|
5.3. Syllabus
The program offered to help the student achieve the expected results includes the following activities:
PROGRAM OF LECTURES
Lectures are divided into 4 thematic blocks, with the timing and assignment of hours listed below.
VI. MICROBIOLOGY AND DISEASE (5 h)
- Unit 1. Health monitoring and disease prevention. Health monitoring programme in experimental units.
- Unit 2. Pathology of common animal laboratory diseases.
- Unit 3. Safety in working with infectious animals.
VII. ANAESTHESIA, ANALGESIA AND EXPERIMENTAL PROCEDURES (9 h)
- Unit 4. Introduction to methods of anaesthesia. Anaesthetics and analgesics. Choice of anaesthetic agent in relation to animal species and nature of experiment.
- Unit 5. Analgesia. Recognition, assessment and control of pain, suffering or distress.
- Unit 6. Euthanasia: chemical and physical methods. Disposal of carcasses.
- Unit 7. Experimental procedures in surgery. Principles of surgery, facilities, surgical equipment, aseptic techniques, special perioperative considerations. Postoperative care and monitoring.
- Unit 8. Refining procedures for the administration of substances. Biological sampling collection.
- Unit 9. Experimental procedures in pharmacology, toxicology, microbiology and infectious diseases.
VIII. Design and conduct of animal experiments (5 h)
- Unit 10. Experimental design. Guidelines for good design. Choice of the experimental animal and power analysis to calculate the number of animals. Statistical analysis and interpretation of results. Designs applied in animal experimentation.
- Unit 11. Animal models (spontaneous, induced).
IX. ANALYSIS AND ELABORATION OF SCIENTIFIC LITERATURE (1 h)
- Unit 12. Analysis and elaboration of scientific literature.
PROGRAM OF PRACTICAL CLASSES
The program consists of 10 hours of practical activities, distributed into 6 sessions:
Only Practice 3 involves working with live animals. This practice has been subjected to prior evaluation by the Advisory Ethics Committee for Animal Experimentation of the University of Zaragoza (License number PD05/14). The carcasses used in Practice 1 and 4 come from animals which have not expressly been euthanized for the practice.
- Practice 1. Necropsy in experimental animals. Technique and sampling. Recognition of macroscopic lesions of organs and tissues in the mouse, rat and rabbit (2 hours).
- Practice 2. Workshop onpain recognition (2 hours).
- Practice 3. Administration of substances. Sample collection in rabbit (1 hour).
- Practice 4. Surgical procedures in experimental surgery (2 hours).
- Practice 5. Workshop on experimental design of procedures (2 hours).
- Practice 6. Evaluation of procedures by ethics committees (1 hour).